Ruo-Hui Tang,Jing Yang,Jun Fei.[J].Chin J Traumatol,2020,23(6):314-318. [doi]
New perspectives on traumatic bone infections
  
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KeyWord: Bone infectionBone destructionOsteoclastsImmunomodulation
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Author NameAffiliation
Ruo-Hui Tang Health Team of 96824 Troops of the Chinese People's Liberation Army, Kunming, China 
Jing Yang Emergency Department, Daping Hospital, Third Military Medical University, Chongqing, China 
Jun Fei State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University, Chongqing, China 
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Abstract:
      In this paper, we review the results of previous studies and summarize the effects of various factors on the regulation of bone metabolism in traumatic bone infections. Infection-related bone destruction incorporates pathogens and iatrogenic factors in the process of bone resorption dominated by the skeletal and immune systems. The development of bone immunology has established a bridge of communication between the skeletal system and the immune system. Exploring the effects of pathogens, skeletal systems, immune systems, and antibacterials on bone repair in infectious conditions can help improve the treatment of these diseases.
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