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| Xiu-Wen Wu,Tao Zheng,Zhi-Wu Hong,Hua-Jian Ren,Lei Wu,Ge-Fei Wang,Guo-Sheng Gu,Jian-An Ren.[J].Chin J Traumatol,2020,23(6):311-313. [doi] |
| Current progress of source control in the management of intra-abdominal infections |
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| DOI： |
| KeyWord: Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Chinab Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China |
| FundProject: |
| Author Name | Affiliation | | Xiu-Wen Wu | Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China | | Tao Zheng | Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China | | Zhi-Wu Hong | Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China | | Hua-Jian Ren | Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China | | Lei Wu | Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China | | Ge-Fei Wang | Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China | | Guo-Sheng Gu | Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China | | Jian-An Ren | Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China |
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| Abstract: |
| Intra-abdominal infection (IAI) is a deadly condition in which the outcome is associated with urgent diagnosis, assessment and management, including fluid resuscitation, antibiotic administration while obtaining further laboratory results, attaining precise measurements of hemodynamic status, and pursuing source control. This last item makes abdominal sepsis a unique treatment challenge. Delayed or inadequate source control is an independent predictor of poor outcomes and recognizing source control failure is often difficult or impossible. Further complicating issue in the debate is surrounding the timing, adequacy, and procedures of source control. This review evaluated and summarized the current approach and challenges in IAI management, which are the future research directions. |
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