Koorosh Ahmadi,Amir Masoud Hashemian,Elham Pishbin,Mahdi Sharif-Alhoseini,Vafa Rahimi-Movaghar.[J].Chin J Traumatol,2014,17(4):204-207. [doi]
Impact of intravenous acetaminophen therapy on the necessity of cervical spine imaging in patients with cervical spine trauma
  
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KeyWord: Acetaminophen  Diagnosis  Spinal Injuries  Cervical vertebrae  Radiography
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Author NameAffiliation
Koorosh Ahmadi Department of Emergency Medicine, Alborz University of Medical Sciences, Karaj, Iran 
Amir Masoud Hashemian Department of Emergency Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 
Elham Pishbin Department of Emergency Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 
Mahdi Sharif-Alhoseini Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran 
Vafa Rahimi-Movaghar Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran
Department of Neurosurgery, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran 
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Abstract:
      Objective: We evaluated a new hypothesis of acetaminophen therapy to reduce the necessity of imaging in patients with probable traumatic cervical spine injury. Methods: Patients with acute blunt trauma to the neck and just posterior midline cervical tenderness received acetaminophen (15 mg/kg) intravenously after cervical spine immobilization. Then, all the patients underwent plain radiography and computerized tomography of the cervical spine. The outcome measure was the presence of traumatic cervical spine injury. Sixty minutes after acetaminophen infusion, posterior midline cervical tenderness was reassessed. Results: Of 1 309 patients, 41 had traumatic cervical spine injuries based on imaging. Sixty minutes after infusion, posterior midline cervical tenderness was eliminated in 1 041 patients, none of whom had abnormal imaging. Conclusion: Patients with cervical spine trauma do not need imaging if posterior midline cervical tenderness is eliminated after acetaminophen infusion. This analgesia could be considered as a diagnostic and therapeutic intervention.
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