Guo Yingjun,Nie Lin,Zhang Wen,Mu Qing.[J].Chin J Traumatol,2014,17(4):198-203. [doi]
Effects of self-blood on the molding process of polymethyl methacrylate bone cement
  
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KeyWord: Plasma  Serum  Polymethyl methacrylate  Hyperlipidemias
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Author NameAffiliation
Guo Yingjun Department of Orthopaedic Surgery, Qilu Hospital of Shandong University, Jinan 250012, China 
Nie Lin Department of Orthopaedic Surgery, Qilu Hospital of Shandong University, Jinan 250013, China 
Zhang Wen Department of Orthopaedic Surgery, Qilu Hospital of Shandong University, Jinan 250014, China 
Mu Qing Department of Orthopaedic Surgery, Qilu Hospital of Shandong University, Jinan 250015, China 
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Abstract:
      Objective: To evaluate whether the self-blood has influence on the molding process of polymethyl methacrylate (PMMA) bone cement, and to make sure whether it is valuable for the clinical practice. Methods: An in vitro study was performed to evaluate the prolonging-effect of self-blood on PMMA bone cement. The effect of prolonging was evaluated by the dough time (TD) and operable time (TO). Moreover, hardness test, squeezing value test and peak temperature test were also conducted to complete the evaluation of this program. Results: The self-blood, especially the plasma, could greatly prolong the handling time of PMMA bone cement without affecting its basic characteristics including hardness, leakage level and peak temperature. On the other hand, we found that in some abnormal conditions, for example with hyperlipemia, self-blood though can also prolong the handling time, would cause some sideeffects. Conclusion: We report a new effective way to prolong the handling time of PMMA bone cement by adding moderate amount of self-blood. But "individualized medicine" should be noticed because some abnormal conditions like hyperlipemia would cause undesired side-effects.
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