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| ZHANG Hui,ZENG Jian-wei,WANG Guang-lin,TU Chong-qi,HUANG Fu-guo,PEI Fu-xing.[J].Chin J Traumatol,2013,16(1):10-15. [doi] |
| Infectious complications in patients withcrush syndrome following the Wenchuan earthquake |
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| DOI： |
| KeyWord: Earthquakes Crushsyndrome Infection Microbial sensitivity tests |
| FundProject: |
| Author Name | Affiliation | | ZHANG Hui | Department of Orthopaedics, West China Hospital,
Sichuan University, Chengdu 610041, China | | ZENG Jian-wei | Department of Orthopaedics, West China Hospital,
Sichuan University, Chengdu 610042, China | | WANG Guang-lin | Department of Orthopaedics, West China Hospital,
Sichuan University, Chengdu 610043, China | | TU Chong-qi | Department of Orthopaedics, West China Hospital,
Sichuan University, Chengdu 610044, China | | HUANG Fu-guo | Department of Orthopaedics, West China Hospital,
Sichuan University, Chengdu 610045, China | | PEI Fu-xing | Department of Orthopaedics, West China Hospital,
Sichuan University, Chengdu 610046, China |
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| Abstract: |
| Objective: To analyze the results of clinical and bacteriological examinations in patients with crush
syndrome who suffered infectious complications after an earthquake in Sichuan, China.
Methods: A total of313 bacteriological samples among 147 patients with crush syndrome were collected. Infectious complications, results of microbiological examinations, potential risk factors of infection and mortality were analyzed statistically.
Results: In the obtained database, 112 out of the 147 (75.7%) patients had infectious complications, in which, wound infection, pulmonary infection, and sepsis were most common. The time under the rubble and the time from injury to treatment were related to the occurrence of wound infection (P=0.013, odds ratio2.25; P=0.017, odds ratio2.31). Sepsis and wound infection were more common in patients who underwent fasciotomy or amputation than in those who did not(P=0.001).
Conclusion: Quick rescue and injury treatment can decrease the infection risk in crush syndrome patients. It is better to obtain microorganic proofs before applying antibiotics, and bacteriological and drug sensitivity data should be taken into account, especially considering that most of these infections are hospital-acquired and drug resistance. Emphasizing the accuracy and efficiency of
wound management in emergency situations, cautiously assessing the indications for fasciotomy to avoid open wounds from unnecessary osteofascial compartment decompression incisions may decrease the incidence of infection and ameliorate the prognosis. |
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